the relaxant effect of nigella sativa on smooth muscles, its possible mechanisms and clinical applications

نویسندگان

rana keyhanmanesh tuberculosis and lung research center, tabriz university of medical sciences, tabriz, iran

zahra gholamnezhad neurogenic inflammation research centre and department of physiology, school of medicine, mashhad university of medical sciences, mashhad, iran

mohammad hossien boskabady neurogenic inflammation research centre and department of physiology, school of medicine, mashhad university of medical sciences, mashhad, iran

چکیده

nigella sativa (n. sativa) is a spice plant which has been traditionally used for culinary and medicinal purposes. different therapeutic properties including the beneficial effects on asthma and dyspnea, digestive and gynecology disorders have been described for the seeds of n. sativa. there is evidence of the relaxant effects of this plant and some of its constituents on different types of smooth muscle including rabbit aorta, rabbit jejunum and trachea. the relaxant effect of n. sativa could be of therapeutic importance such as bronchodilation in asthma, vasodilation in hypertension and therapeutic effect on digestive or urogenital disorders. therefore in the present article, the relaxant effects of n. sativa and its constituents on smooth muscles and its possible mechanisms as well as clinical application of this effect were reviewed.

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منابع مشابه

The relaxant effect of Nigella sativa on smooth muscles, its possible mechanisms and clinical applications

Nigella sativa (N. sativa) is a spice plant which has been traditionally used for culinary and medicinal purposes. Different therapeutic properties including the beneficial effects on asthma and dyspnea, digestive and gynecology disorders have been described for the seeds of N. sativa. There is evidence of the relaxant effects of this plant and some of its constituents on different types of smo...

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The relaxant effect of Nigella sativa on smooth muscles, its possible mechanisms and clinical applications

Nigella sativa (N. sativa) is a spice plant which has been traditionally used for culinary and medicinal purposes. Different therapeutic properties including the beneficial effects on asthma and dyspnea, digestive and gynecology disorders have been described for the seeds of N. sativa. There is evidence of the relaxant effects of this plant and some of its constituents on different types of smo...

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The Relaxant Effect of Crocin on Rat Tracheal Smooth Muscle and Its Possible Mechanisms

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The Relaxant Effect of Crocin on Rat Tracheal Smooth Muscle and Its Possible Mechanisms

Crocin, a component of saffron, showed hypotensive which is perhaps due to vascular smooth muscle relaxant effect. The relaxant effects of saffron on tracheal smooth muscle also could be due to its constituent, crocin. In the present study, the relaxant effects of crocin and its possible mechanisms on rat tracheal smooth muscle were investigated. The relaxant effects of three cumulative concent...

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Smooth muscle relaxant activity of Crocus sativus (saffron) and its constituents: possible mechanisms

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Smooth muscle relaxant activity of Crocus sativus (saffron) and its constituents: possible mechanisms

We praise the article by Mokhtari-Zaer et al. (2015) published in the Avicenna Journal of Phytomedicine on the effects of saffron on smooth muscle activity (Mokhtari-Zaer et al., 2015). It was a well-designed and interesting study on the therapeutic properties of Crocus sativus which is a precious plant cultivated in our country. We do believe that along with all other medicinal effects, saffro...

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عنوان ژورنال:
iranian journal of basic medical sciences

جلد ۱۷، شماره ۱۲، صفحات ۹۳۹-۹۴۹

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